Synthesis of new, BODIPY-based sensors and labels

被引：50

作者：

Kalai, Tamas ^{[1
]}

Hideg, Kalman ^{[1
]}

机构：

[1] Univ Pecs, Inst Organ & Med Chem, H-7602 Pecs, Hungary

来源：

TETRAHEDRON | 2006年 / 62卷 / 44期

基金：

匈牙利科学研究基金会;

关键词：

fluorescence; crown ethers; amino acid; nitroxides; double sensors;

D O I：

10.1016/j.tet.2006.08.079

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New, 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dye based thiol-reactive fluorescent label, fluorescent amino acid, and fluoroionophore compounds with 540-560 mn emission are described. Combination of a BODIPY dye with a nitronyl nitroxide or an imino nitroxide or a bifunctional pyrroline nitroxide furnished a nitric oxide, a redox sensitive molecule and a double (spin and fluorescence) label, respectively. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：10352 / 10360

页数：9

共 49 条

[1]

[Anonymous], [No title captured]

[2] Proton controlled intramolecular photoinduced electron transfer (PET) in podand linked squaraine-aniline dyads [J].

Arunkumar, E ;

Ajayaghosh, A .

CHEMICAL COMMUNICATIONS, 2005, (05) :599-601

[3] Synthesis of new conformationally rigid paramagnetic α-amino acids [J].

Balog, M ;

Kálai, T ;

Jeko, J ;

Berente, Z ;

Steinhoff, HJ ;

Engelhard, M ;

Hideg, K .

TETRAHEDRON LETTERS, 2003, 44 (51) :9213-9217

[4] Synthesis of new 2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxyl radicals and 2-substituted-2,5,5-trimethylpyrrolidin-1-yloxyl radicals based α-amino acids [J].

Balog, MR ;

Kálai, TK ;

Jekö, J ;

Steinhoff, HJ ;

Engelhard, M ;

Hideg, K .

SYNLETT, 2004, (14) :2591-2593

[5] A highly potassium-selective ratiometric fluorescent indicator based on BODIPY azacrown ether excitable with visible light [J].

Baruah, M ;

Qin, WW ;

Vallée, RAL ;

Beljonne, D ;

Rohand, T ;

Dehaen, W ;

Boens, N .

ORGANIC LETTERS, 2005, 7 (20) :4377-4380

[6] Incorporation of spin-labelled amino acids into proteins [J].

Becker, CFW ;

Lausecker, K ;

Balog, M ;

Kálai, T ;

Hideg, K ;

Steinhoff, HJ ;

Engelhard, M .

MAGNETIC RESONANCE IN CHEMISTRY, 2005, 43 (43) :S34-S39

[7] A NOVEL REVERSIBLE THIOL-SPECIFIC SPIN LABEL - PAPAIN ACTIVE-SITE LABELING AND INHIBITION [J].

BERLINER, LJ ;

GRUNWALD, J ;

HANKOVSZKY, HO ;

HIDEG, K .

ANALYTICAL BIOCHEMISTRY, 1982, 119 (02) :450-455

[8] Interaction of singlet molecular oxygen with double fluorescent and spin sensors [J].

Bilski, P ;

Hideg, K ;

Kálai, T ;

Bilska, MA ;

Chignell, CF .

FREE RADICAL BIOLOGY AND MEDICINE, 2003, 34 (04) :489-495

[9] Synthesis of new double (spin and fluorescence) sensor reagents and labels [J].

Bognár, B ;

Osz, E ;

Hideg, K ;

Kálai, T .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2006, 43 (01) :81-86

[10] ION-RESPONSIVE FLUORESCENT COMPOUNDS .4. EFFECT OF CATION BINDING ON THE PHOTOPHYSICAL PROPERTIES OF A COUMARIN LINKED TO MONOAZA-CROWN AND DIAZA-CROWN ETHERS [J].

BOURSON, J ;

POUGET, J ;

VALEUR, B .

JOURNAL OF PHYSICAL CHEMISTRY, 1993, 97 (17) :4552-4557

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