Electrochemical detection of glutathione: An electrochemically initiated reaction pathway

被引：33

作者：

Seymour, EH ^{[1
]}

Wilkins, SJ ^{[1
]}

Lawrence, NS ^{[1
]}

Compton, RG ^{[1
]}

机构：

[1] Univ Oxford, Phys & Theoret Chem Lab, Oxford OX1 3QZ, England

来源：

ANALYTICAL LETTERS | 2002年 / 35卷 / 08期

基金：

英国工程与自然科学研究理事会;

关键词：

glutathione; catechol; electrochemistry; square wave voltammetry;

D O I：

10.1081/AL-120006674

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The electrochemically initiated reaction of glutathione with catechol in aqueous phosphate buffer has been examined as a facile route to the selective electrochemical determination of the former in the presence of other potential interferents (including cysteine, homocysteine). The results provide a linear detection range of 1-80 muM for glutathione with a corresponding limit of detection of 0.94 muM. The efficacy of the approach hag been shown by the 104% (RSD = 7.3%, N = 3) recovery of 10 muM glutathione in a growth tissue media containing a number of important biomarkers.

引用

页码：1387 / 1399

页数：13

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