Glycogen synthase: Key effect of exercise on insulin action

被引:23
作者
Christ-Roberts, CY
Mandarino, LJ
机构
[1] Univ Texas, Hlth Sci Ctr, Dept Med, Div Diabet MC 7886, San Antonio, TX 78229 USA
[2] Univ Texas, Hlth Sci Ctr, Dept Biochem, San Antonio, TX 78284 USA
[3] Univ Texas, Hlth Sci Ctr, Dept Physiol, San Antonio, TX 78284 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2004年 / 32卷 / 03期
关键词
glucose uptake; diabetes; physical activity; skeletal muscle;
D O I
10.1097/00003677-200407000-00003
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Exercise improves insulin action in muscle, but the mechanisms are poorly characterized. Despite the notion that increased insulin signaling would accompany improved insulin sensitivity, this is not universally true. Increased activity or expression of other proteins seems to be more important. An increase in activity and expression of glycogen synthase and GLUT4 may be key to the effects of exercise.
引用
收藏
页码:90 / 94
页数:5
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