From primary structure to function: biological insights from large-molecule mass spectra

被引:26
作者
Kelleher, NL [1 ]
机构
[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA
来源
CHEMISTRY & BIOLOGY | 2000年 / 7卷 / 02期
关键词
D O I
10.1016/S1074-5521(00)00081-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
As increasing information is available from genomic databases, mass spectrometry has begun to be used to identify and/or assess regions of predicted DNA or protein sequence. Mass spectrometry performance limits, together with experiments designed for genomic interplay, are being extended to allow accurate genotyping and protein profiling of cells at rates commensurate with the data-intensive future of biology.
引用
收藏
页码:R37 / R45
页数:9
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