MMDB: 3D structure data in Entrez

被引：33

作者：

Wang, YL ^{[1
]}

Addess, KJ ^{[1
]}

Geer, L ^{[1
]}

Madej, T ^{[1
]}

Marchler-Bauer, A ^{[1
]}

Zimmerman, D ^{[1
]}

Bryant, SH ^{[1
]}

机构：

[1] NIH, Natl Lib Med, Natl Ctr Biotechnol Informat, Bethesda, MD 20894 USA

来源：

NUCLEIC ACIDS RESEARCH | 2000年 / 28卷 / 01期

关键词：

D O I：

10.1093/nar/28.1.243

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three-dimensional structures are now known for roughly half of all protein families. It is thus quite likely, in searching sequence databases, that one will encounter a homolog with known structure and be able to use this information to infer structure-function properties. The goal of Entrez's 3D structure database is to make this information accessible and useful to molecular biologists, To this end, Entrez's search engine provides three powerful features: (i) Links between databases; one may search by term matching in Medline(R), for example, and link to 3D structures reported in these articles, (ii) Sequence and structure neighbors; one may select all sequences similar to one of interest, for example, and link to any known 3D structures, (iii) Sequence and structure visualization; identifying a homolog with known structure, one may view a combined molecular-graphic and alignment display, to infer approximate 3D structure. Entrez's MMDB (Molecular Modeling DataBase) may be accessed at: http://www.ncbi.nlm.nih.gov/Entrez/structure.html.

引用

页码：243 / 245

页数：3

共 9 条

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