IL-23R gene polymorphism rs2201841 is associated with psoriatic arthritis

被引：16

作者：

Popadic, S. ^{[1
,2
]}

Ramic, Z. ^{[3
]}

Medenica, Lj. ^{[1
,2
]}

Pravica, V. ^{[3
]}

Popadic, D. ^{[3
]}

机构：

[1] Univ Belgrade, Sch Med, Dept Dermatovenereol, Belgrade 11000, Serbia

[2] Clin Ctr Serbia, Clin Dermatovenereol, Belgrade, Serbia

[3] Univ Belgrade, Sch Med, Inst Microbiol & Immunol, Belgrade 11000, Serbia

来源：

INTERNATIONAL JOURNAL OF IMMUNOGENETICS | 2014年 / 41卷 / 04期

关键词：

IL23R; SUSCEPTIBILITY; METAANALYSIS; RECEPTOR; DISEASE; CELLS;

D O I：

10.1111/iji.12127

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学];

摘要：

We examined rs2201841 within IL-23R gene in Serbian patients with psoriasis and healthy controls. G allele frequency was significantly increased in the group of patients with psoriatic arthritis compared with controls (0.481 vs 0.308). Carriage of G allele increases risk to develop psoriatic arthritis (P = 0.009, OR = 3.311, 95% CI 1.29-8.70).

引用

页码：335 / 337

页数：3

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