Candida antarctica lipase B:: An ideal biocatalyst for the preparation of nitrogenated organic compounds

被引:321
作者
Gotor-Fernandez, Vicente [1 ]
Busto, Eduardo [1 ]
Gotor, Vicente [1 ]
机构
[1] Univ Oviedo, Fac Quim, Dept Quim Organ & Inorgan, E-33006 Oviedo, Spain
关键词
amides; amines; aminolysis; ammonolysis; Candida antarctica lipase B; enzymatic resolution;
D O I
10.1002/adsc.200606057
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Candida antarctica lipase B (CAL-B) is a very effective catalyst for the production of amines and amides using different enzymatic procedures. Simplicity of use, low cost, commercial availability and recycling possibility make this lipase an ideal tool for the synthesis and resolution of a wide range of nitrogenated compounds that can be used for the production of pharmaceuticals and interesting manufactures in the industrial sector.
引用
收藏
页码:797 / 812
页数:16
相关论文
共 109 条
[81]   VINYL CARBONATES AS NOVEL ALKOXYCARBONYLATION REAGENTS IN ENZYMATIC-SYNTHESIS OF CARBONATES [J].
POZO, M ;
PULIDO, R ;
GOTOR, V .
TETRAHEDRON, 1992, 48 (31) :6477-6484
[82]   DOUBLE ENANTIOSELECTIVE ENZYMATIC-SYNTHESIS OF CARBONATES AND URETHANES [J].
POZO, M ;
GOTOR, V .
TETRAHEDRON-ASYMMETRY, 1995, 6 (11) :2797-2802
[83]   Solvent-free biocatalytic amidation of carboxylic acids [J].
Prasad, AK ;
Husain, M ;
Singh, BK ;
Gupta, RK ;
Manchanda, VK ;
Olsen, CE ;
Parmar, VS .
TETRAHEDRON LETTERS, 2005, 46 (26) :4511-4514
[84]   Enantioselective enzymatic aminolysis and ammonolysis of dimethyl 3-hydroxyglutarate. Synthesis of (R)-4-amino-3-hydroxybutanoic acid [J].
Puertas, S ;
Rebolledo, F ;
Gotor, V .
JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (17) :6024-6027
[85]  
Reetz MT, 1996, CHIMIA, V50, P668
[86]   Lipases as practical biocatalysts [J].
Reetz, MT .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (02) :145-150
[87]   Molecular recognition of sec-alcohol enantiomers by Candida antarctica lipase B [J].
Rotticci, D ;
Haeffner, F ;
Orrenius, C ;
Norin, T ;
Hult, K .
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 1998, 5 (1-4) :267-272
[88]   Candida antarctica lipase catalyzed resolution of ethyl (+/-)-3-aminobutyrate [J].
Sanchez, VM ;
Rebolledo, F ;
Gotor, V .
TETRAHEDRON-ASYMMETRY, 1997, 8 (01) :37-40
[89]   Candida antarctica lipase-catalyzed doubly enantioselective aminolysis reactions.: Chemoenzymatic synthesis of 3-hydroxypyrrolidines and 4-(silyloxy)-2-oxopyrrolidines with two stereogenic centers [J].
Sánchez, VM ;
Rebolledo, F ;
Gotor, V .
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (05) :1464-1470
[90]  
Schmidt M, 2004, METHOD ENZYMOL, V388, P199