A diaminochlorophosphine for palladium-catalyzed arylations of amines and ketones

被引：95

作者：

Ackermann, Lutz ^{[1
]}

Spatz, Julia H. ^{[1
]}

Gschrei, Christian J. ^{[1
]}

Born, Robert ^{[1
]}

Althammer, Andreas ^{[1
]}

机构：

[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 45期

关键词：

arylation; C-N coupling; cross-coupling; palladium; phosphane ligands;

D O I：

10.1002/anie.200602222

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Sterically hindered substituents on a secondary chlorophosphine 1 prevent formation of a diaminooxophosphine, and thereby allow for highly efficient arylation reactions of amines and α-C-H acidic ketones with (hetero)aryl chlorides. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7627 / 7630

页数：4

共 35 条

[21] Jiang L., 2004, Metal-Catalyzed Cross-Coupling Reactions, P699, DOI DOI 10.1002/9783527619535.CH13
[22] Li G. Y., 2001, ANGEW CHEM, V113, P1561
[23] Highly active, air-stable versatile palladium catalysts for the C-C, C-N, and C-S bond formations via cross-coupling reactions of aryl chlorides
Li, GY
Zheng, G
Noonan, AF
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (25) : 8677 - 8681
[24] Li GY, 2001, ANGEW CHEM INT EDIT, V40, P1513, DOI 10.1002/1521-3773(20010417)40:8<1513::AID-ANIE1513>3.0.CO
[25] 2-C
[26] Transition metal complexes bearing a phosphenium ligand
Nakazawa, H
[J]. ADVANCES IN ORGANOMETALLIC CHEMISTRY, VOL. 50, 2004, 50 : 107 - 143
[27] Synthesis of N-arylpiperazines from aryl halides and piperazine under a palladium tri-tert-butylphosphine catalyst
Nishiyama, M
Yamamoto, T
Koie, Y
[J]. TETRAHEDRON LETTERS, 1998, 39 (07) : 617 - 620
[28] New ligands for a general palladium-catalyzed amination of aryl and heteroaryl chlorides
Rataboul, F
Zapf, A
Jackstell, R
Harkal, S
Riermeier, T
Monsees, A
Dingerdissen, U
Beller, M
[J]. CHEMISTRY-A EUROPEAN JOURNAL, 2004, 10 (12) : 2983 - 2990
[29] Palladium-catalyzed C-N and C-O coupling - A practical guide from an industrial vantage point
Schlummer, B
Scholz, U
[J]. ADVANCED SYNTHESIS & CATALYSIS, 2004, 346 (13-15) : 1599 - 1626
[30] Shen Q., 2005, ANGEW CHEM, V117, P1395

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