Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands

被引：56

作者：

Abuskhuna, S

Briody, J

McCann, M ^{[1
]}

Devereux, M

Kavanagh, K

Fontecha, JB

McKee, V

机构：

[1] Natl Univ Ireland Maynooth, St Patricks Coll, Dept Chem, Maynooth, Kildare, Ireland

[2] Dublin Inst Technol, Dublin, Ireland

[3] Natl Univ Ireland Maynooth, Dept Biol, Maynooth, Kildare, Ireland

[4] Univ Loughborough, Dept Chem, Loughborough LE11 3TU, Leics, England

来源：

POLYHEDRON | 2004年 / 23卷 / 07期

关键词：

bis-imidazole; bis(imidazol-2-yl)methane; X-ray structures; silver(I); argentophilicity; anti-fungal; Candida albicans;

D O I：

10.1016/j.poly.2004.02.006

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

;ive Ag(I) complexes containing the ligands bis(imidazol-2-yl)methane (2-BIM) and its derivatives were prepared and [Ag-2(2-BIM)(2)](ClO4)(2) and [Ag-2(2-BIM(Bz)OH)(2)](ClO4)(2) . EtOH were characterised using X-ray crystallography. In each dimer the two Ag(I) ions are two-coordinate and there are small but definite argentophilic Ag-Ag (d(10)-d(10)) interactions. All of the complexes display anti-fungal activity when tested in vitro against the fungal pathogen Candida albicans. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1249 / 1255

页数：7

共 18 条

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