Asymmetric synthesis of monodentate phosphine ligands based on chiral η6-Cr[arene] templates

被引：56

作者：

Nelson, SG ^{[1
]}

Hilfiker, MA ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 09期

关键词：

D O I：

10.1021/ol990929s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Optically active Cr-complexed arylphosphines are presented as a new class of chiral monodentate phosphine ligand for use in asymmetric catalysis, Asymmetric synthesis of the chiral phosphine ligands 9 is achieved in three steps from the achiral Cr[arene] precursor 3. A variety of ligand structures are accessed from a common synthesis intermediate. The utility of these phosphine ligands in asymmetric catalysis is highlighted in Pd(II)-catalyzed allylic alkylation reactions.

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页码：1379 / 1382

页数：4

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