Pericytes or Mesenchymal Stem Cells: Is That the Question?

被引：47

作者：

Cano, Elena ^{[1
,2
]}

Gebala, Veronique ^{[1
,2
]}

Gerhardt, Holger ^{[1
,2
,3
,4
]}

机构：

[1] Helmholtz Assoc MDC, Max Delbruck Ctr Mol Med, Integrat Vasc Biol Lab, Robert Rossle Str 10, D-13125 Berlin, Germany

[2] Partner Site Berlin, DZHK German Ctr Cardiovasc Res, Berlin, Germany

[3] BIH, Kapelle Ufer 2, D-10117 Berlin, Germany

[4] Katholieke Univ Leuven, Vasc Patterning Lab, Ctr Canc Biol, VIB,Dept Oncol, Herestr 49, B-3000 Leuven, Belgium

来源：

CELL STEM CELL | 2017年 / 20卷 / 03期

关键词：

PRECURSORS; ORIGIN;

D O I：

10.1016/j.stem.2017.02.005

中图分类号：

Q813 [细胞工程];

学科分类号：

100113 [医学细胞生物学];

摘要：

For almost a decade, mesenchymal stem cells (MSCs) were believed to reside as perivascular cells in vivo. In this issue of Cell Stem Cell, Guimaraes-Camboa et al. (2017) challenge this idea and use lineage tracing to demonstrate that perivascular cells do not behave as tissue-specific progenitors in various organs, despite showing MSC potential in vitro.

引用

页码：296 / 297

页数：3

共 10 条

[1]

"Mesenchymal" Stem Cells [J].

Bianco, Paolo .

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30, 2014, 30 :677-704

[2]

Human Myocardial Pericytes: Multipotent Mesodermal Precursors Exhibiting Cardiac Specificity [J].

Chen, William C. W. ;

Baily, James E. ;

Corselli, Mirko ;

Diaz, Mary E. ;

Sun, Bin ;

Xiang, Guosheng ;

Gray, Gillian A. ;

Huard, Johnny ;

Peault, Bruno .

STEM CELLS, 2015, 33 (02) :557-573

[3]

A perivascular origin for mesenchymal stem cells in multiple human organs [J].

Crisan, Mihaela ;

Yap, Solomon ;

Casteilla, Louis ;

Chen, Chien-Wen ;

Corselli, Mirko ;

Park, Tea Soon ;

Andriolo, Gabriella ;

Sun, Bin ;

Zheng, Bo ;

Zhang, Li ;

Norotte, Cyrille ;

Teng, Pang-Ning ;

Traas, Jeremy ;

Schugar, Rebecca ;

Deasy, Bridget M. ;

Badylak, Stephen ;

Buehring, Hans-Joerg ;

Giacobino, Jean-Paul ;

Lazzari, Lorenza ;

Huard, Johnny ;

Peault, Bruno .

CELL STEM CELL, 2008, 3 (03) :301-313

[4]

Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells [J].

Dellavalle, Arianna ;

Sampaolesi, Maurilio ;

Tonlorenzi, Rossana ;

Tagliafico, Enrico ;

Sacchetti, Benedetto ;

Perani, Laura ;

Innocenzi, Anna ;

Galvez, Beatriz G. ;

Messina, Graziella ;

Morosetti, Roberta ;

Li, Sheng ;

Belicchi, Marzia ;

Peretti, Giuseppe ;

Chamberlain, Jeffrey S. ;

Wright, Woodring E. ;

Torrente, Yvan ;

Ferrari, Stefano ;

Bianco, Paolo ;

Cossu, Giulio .

NATURE CELL BIOLOGY, 2007, 9 (03) :255-U30

[5]

Dual origin of mesenchymal stem cells contributing to organ growth and repair [J].

Feng, Jifan ;

Mantesso, Andrea ;

De Bari, Cosimo ;

Nishiyama, Akiko ;

Sharpe, Paul T. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (16) :6503-6508

[6]

A Pericyte Origin of Spinal Cord Scar Tissue [J].

Goritz, Christian ;

Dias, David O. ;

Tomilin, Nikolay ;

Barbacid, Mariano ;

Shupliakov, Oleg ;

Frisen, Jonas .

SCIENCE, 2011, 333 (6039) :238-242

[7]

Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo [J].

Guimaraes-Camboa, Nuno ;

Cattaneo, Paola ;

Sun, Yunfu ;

Moore-Morris, Thomas ;

Gu, Yusu ;

Dalton, Nancy D. ;

Rockenstein, Edward ;

Masliah, Eliezer ;

Peterson, Kirk L. ;

Stallcup, William B. ;

Chen, Ju ;

Evans, Sylvia M. .

CELL STEM CELL, 2017, 20 (03) :345-+

[8]

Follicular Dendritic Cells Emerge from Ubiquitous Perivascular Precursors [J].

Krautler, Nike Julia ;

Kana, Veronika ;

Kranich, Jan ;

Tian, Yinghua ;

Perera, Dushan ;

Lemm, Doreen ;

Schwarz, Petra ;

Armulik, Annika ;

Browning, Jeffrey L. ;

Tallquist, Michelle ;

Buch, Thorsten ;

Oliveira-Martins, Jose B. ;

Zhu, Caihong ;

Hermann, Mario ;

Wagner, Ulrich ;

Brink, Robert ;

Heikenwalder, Mathias ;

Aguzzi, Adriano .

CELL, 2012, 150 (01) :194-206

[9]

Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment [J].

Sacchetti, Benedetto ;

Funari, Alessia ;

Michienzi, Stefano ;

Di Cesare, Silvia ;

Piersanti, Stefania ;

Saggio, Isabella ;

Tagliafico, Enrico ;

Ferrari, Stefano ;

Robey, Pamela Gehron ;

Riminucci, Mara ;

Bianco, Paolo .

CELL, 2007, 131 (02) :324-336

[10]

White fat progenitor cells reside in the adipose vasculature [J].

Tang, Wei ;

Zeve, Daniel ;

Suh, Jae Myoung ;

Bosnakovski, Darko ;

Kyba, Michael ;

Hammer, Robert E. ;

Tallquist, Michelle D. ;

Graff, Jonathan M. .

SCIENCE, 2008, 322 (5901) :583-586

← 1 →