Techniques: Cardiovascular pharmacology and drug discovery in the 21st century

被引：7

作者：

Douglas, SA ^{[1
]}

Ohlstein, EH ^{[1
]}

Johns, DG ^{[1
]}

机构：

[1] GlaxoSmithKline, Cardiovasc & Urogenital Ctr Excellence Drug Disco, Vasc Thombosis & Inflammat UW2510, King Of Prussia, PA 19406 USA

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 2004年 / 25卷 / 04期

关键词：

D O I：

10.1016/j.tips.2004.02.013

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The latter half of the 20th century has been characterized by pharmacologists as the 'age of the receptor', an era in which the bioassay, that stalwart of classical pharmacology, has played a seminal role in identifying novel cardiovascular medicines. In this article, we ask what, if anything, has changed in the pharmacologist's approach to discovering novel cardiovascular drugs on this, the 25th anniversary of the inaugural publication of Trends in Pharmacological Sciences.

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页码：225 / 233

页数：9

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