A comparison of phenyl- and naphthyl-substituted tris(macrocycle), cation-conducting channels to assess the effect of extended aromaticity

被引：9

作者：

Maguire, GEM

Meadows, ES

Murray, CL

Gokel, GW

机构：

[1] WASHINGTON UNIV,SCH MED,BIOORGAN CHEM PROGRAM,ST LOUIS,MO 63110

[2] WASHINGTON UNIV,SCH MED,DEPT MOL BIOL & PHARMACOL,ST LOUIS,MO 63110

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 36期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(97)01458-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two sodium-cation-conducting, tris(macrocycle) channels, differing only in the size of the terminal aryl groups, have been prepared, characterized, and shown by the planar bilayer conductance method to exhibit qualitative differences in channel activity attributable to the pi-electron surface area difference. (C) 1997 Elsevier Science Ltd.

引用

页码：6339 / 6342

页数：4

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[2]

ANDERSEN OS, 1986, ION CHANNEL RECONSTI, pCH15

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