Tularemia:: Current epidemiology and disease management

被引:85
作者
Eliasson, Henrik
Broman, Tina
Forsman, Mats
Back, Erik
机构
[1] Orebro Univ Hosp, Dept Infect Dis, Infektionskliniken, SE-70185 Orebro, Sweden
[2] Swedish Def Res Agcy, Dept NBC Anal, FOI, SE-90182 Umea, Sweden
[3] Univ Orebro, Dept Clin Med, S-70130 Orebro, Sweden
关键词
D O I
10.1016/j.idc.2006.03.002
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Tularemia, caused by the gram-negative bacterium Francisella tularensis, a zoonosis with a complex epidemiology, is transmitted to humans by vectors, direct contact, inhalation, or the alimentary route. Increasing knowledge, on the subspecies level, of pathogenicity, ecology, and epidemiology is being elucidated as a result of intensified research. A low infective dose of the bacterium in combination with a high attack rate via the respiratory route causes concern over its possible use as a bioterrorism agent. Fluoroquinolone therapy is an alternative to aminoglycoside treatment.
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页码:289 / +
页数:24
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