Asymmetric 1,3-dipolar cycloadditions of cyclic stabilized ylides derived from chiral 1,2-amino alcohols

被引：93

作者：

Bonin, Martine ^{[1
]}

Chauveau, Ariane ^{[1
]}

Micouin, L. ^{[1
]}

机构：

[1] Univ Paris 05, CNRS, UMR 8638, Lab Chim Therapeut,Fac Sci Pharmaceut & Biol, F-75270 Paris 06, France

来源：

SYNLETT | 2006年 / 15期

关键词：

cycloadditions; ylides; stereoselective synthesis; heterocycles; multicomponent reactions;

D O I：

10.1055/s-2006-949626

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of structurally similar chiral non-racemic azomethine ylides, nitrones and azomethine imines derived from 1,2-aminol alcohols in asymmetric dipolar cycloadditions is reviewed. This general survey underlines the great synthetic potential of dipolar cycloadditions, especially in a diversity-oriented approach and enables a direct comparison of the reactivity of apparently closely related reactive systems.

引用

页码：2349 / 2363

页数：15

共 66 条

[41] Synthesis of (5R)-4-Methyl-5-phenyl-1,3,4-oxadiazinan-2-one and some N-acyl derivatives from (R)-phenylglycine [J].