Convenient, in situ generation of anhydrous hydrogen iodide for the preparation of α-glycosyl iodides and vicinal iodohydrins and for the catalysis of Ferrier glycosylation

被引：40

作者：

Chervin, SM ^{[1
]}

Abada, P ^{[1
]}

Koreeda, M ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 03期

关键词：

D O I：

10.1021/ol991312d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Anhydrous hydrogen iodide is generated in situ by the reaction of solid iodine and a thiol, The HI thus generated has been employed for the efficient preparation of alpha-glycosyl iodides and vicinal iodohydrins from the corresponding glycosyl acetates and epoxides, respectively, and for Ferrier glycosylation of alcohols and thiols.

引用

页码：369 / 372

页数：4

共 36 条

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