Sulfonylureas

被引：78

作者：

Zimmerman, BR ^{[1
]}

机构：

[1] MAYO CLIN & MAYO FDN, DEPT ENDOCRINOL, MAYO MED SCH, ROCHESTER, MN 55905 USA

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 1997年 / 26卷 / 03期

关键词：

D O I：

10.1016/S0889-8529(05)70264-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sulfonylureas have been available for the treatment of non-insulin-dependent diabetes mellitus (NIDDM) since the 1950s. With the introduction of new oral agents, there is a tendency to discount the value of sulfonylurea therapy. Sulfonylureas have the advantage of multiple formulations, low costs, minimal side effects, and demonstrated efficacy in controlling hyperglycemia. The major disadvantage of sulfonylureas is secondary failure, which may occur with all oral agents as part of the progression of NIDDM. Sulfonylureas should continue to play an important role in the treatment of NIDDM.

引用

页码：511 / +

页数：1

共 59 条

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