Circadian variation in BDNF mRNA expression in the rat hippocampus

被引:64
作者
Schaaf, MJM [1 ]
Duurland, R [1 ]
de Kloet, ER [1 ]
Vreugdenhil, E [1 ]
机构
[1] Leiden Amsterdam Ctr Drug Res, Sylvius Labs, Div Med Pharmacol, NL-2300 RA Leiden, Netherlands
来源
MOLECULAR BRAIN RESEARCH | 2000年 / 75卷 / 02期
关键词
neurotrophin; neurotrophic factor; diurnal; corticosterone; glucocorticoid;
D O I
10.1016/S0169-328X(99)00314-9
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
BDNF mRNA levels in the hippocampus were studied during the circadian cycle by in situ hybridization. These levels display a circadian pattern, which may be due to regulation by corticosterone. This may have consequences for hippocampal functioning at different time points of the circadian cycle. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:342 / 344
页数:3
相关论文
共 12 条
[1]   BDNF and trkB mRNAs oscillate in rat brain during the light-dark cycle [J].
Bova, R ;
Micheli, MR ;
Qualadrucci, P ;
Zucconi, GG .
MOLECULAR BRAIN RESEARCH, 1998, 57 (02) :321-324
[2]   GLUCOCORTICOIDS AND THE EXPRESSION OF MESSENGER-RNAS FOR NEUROTROPHINS, THEIR RECEPTORS AND GAP-43 IN THE RAT HIPPOCAMPUS [J].
CHAO, HM ;
MCEWEN, BS .
MOLECULAR BRAIN RESEARCH, 1994, 26 (1-2) :271-276
[3]   LONG-LASTING NEUROTROPHIN-INDUCED ENHANCEMENT OF SYNAPTIC TRANSMISSION IN THE ADULT HIPPOCAMPUS [J].
KANG, HJ ;
SCHUMAN, EM .
SCIENCE, 1995, 267 (5204) :1658-1662
[4]   Circadian rhythm of brain-derived neurotrophic factor in the rat suprachiasmatic nucleus [J].
Liang, FQ ;
Walline, R ;
Earnest, DJ .
NEUROSCIENCE LETTERS, 1998, 242 (02) :89-92
[5]   NEUROTROPHINS AND BRAIN INSULTS [J].
LINDVALL, O ;
KOKAIA, Z ;
BENGZON, J ;
ELMER, E ;
KOKAIA, M .
TRENDS IN NEUROSCIENCES, 1994, 17 (11) :490-496
[6]  
Lowenstein DH, 1996, J NEUROSCI, V16, P1759
[7]   Administration of corticosterone alters intracellular localization of brain-derived neurotrophic factor-like immunoreactivity in the rat brain [J].
Nitta, A ;
Fukumitsu, H ;
Kataoka, H ;
Nomoto, H ;
Furukawa, S .
NEUROSCIENCE LETTERS, 1997, 226 (02) :115-118
[8]   Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone [J].
Schaaf, MJM ;
de Jong, J ;
de Kloet, ER ;
Vreugdenhil, E .
BRAIN RESEARCH, 1998, 813 (01) :112-120
[9]   Comparative study of brain-derived neurotrophic factor messenger RNA and protein at the cellular level suggests multiple roles in hippocampus, striatum and cortex [J].
SchmidtKastner, R ;
Wetmore, C ;
Olson, L .
NEUROSCIENCE, 1996, 74 (01) :161-183
[10]   STRESS AND GLUCOCORTICOIDS AFFECT THE EXPRESSION OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND NEUROTROPHIN-3 MESSENGER-RNAS IN THE HIPPOCAMPUS [J].
SMITH, MA ;
MAKINO, S ;
KVETNANSKY, R ;
POST, RM .
JOURNAL OF NEUROSCIENCE, 1995, 15 (03) :1768-1777