Temperature-regulated expression of bacterial virulence genes

被引：195

作者：

Konkel, ME ^{[1
]}

Tilly, K

机构：

[1] Washington State Univ, Sch Mol Biosci, Pullman, WA 99164 USA

[2] NIAID, Rocky Mt Labs, Lab Microbial Struct & Funct, Hamilton, MT 59840 USA

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 02期

关键词：

temperature; virulence; gene regulation;

D O I：

10.1016/S1286-4579(00)00272-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Virulence gene expression in most bacteria is a highly regulated phenomenon, affected by a variety of parameters including osmolarity, pH, ion concentration, iron levels, growth phase, and population density. Virulence genes are also regulated by temperature, which acts as an 'on-off switch in a manner distinct from the more general heat-shock response. Here, we review temperature-responsive expression of virulence genes in four diverse pathogens. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

页码：157 / 166

页数：10

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