Perspectives on the role of ultrasonic devices in thrombolysis

被引:28
作者
Atar, S
Rosenschein, U
机构
[1] Bnai Zion Med Ctr, IL-31048 Haifa, Israel
[2] HaEmek Med Ctr, Afula, Israel
关键词
ultrasonic devices; ultrasound; thrombolysis;
D O I
10.1023/B:THRO.0000037665.21691.61
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Reperfusion strategies in acute myocardial infarction and thrombotic vascular occlusion are focused on rapid and complete restoration of antegrade flow in the infarct-related artery in order to maximize myocardial salvage. Due to the limitations of fibrinolytic agents in restoration of vascular flow, ultrasonic clot dissolution alone and concomitantly with fibrinolytic, anti-thrombotic and echocardiographic contrast agents has been intensively studied during the last 2 decades. Ultrasound thrombolysis has been tested in-vitro and in-vivo as well as in patients with acute thrombotic occlusions. We review currently available techniques and methods of ultrasonic thrombolysis and present recent clinical and experimental data. The future role of ultrasonic thrombolysis and the strategy of "power thrombectomy" for treatment of acute coronary syndromes is also discussed.
引用
收藏
页码:107 / 114
页数:8
相关论文
共 34 条
[1]   DISSOLUTION OF PERIPHERAL ARTERIAL THROMBI BY ULTRASOUND [J].
ARIANI, M ;
FISHBEIN, MC ;
CHAE, JS ;
SADEGHI, H ;
MICHAEL, TAD ;
DUBIN, SB ;
SIEGEL, RJ .
CIRCULATION, 1991, 84 (04) :1680-1688
[2]  
Atar S, 2001, J ENDOVASC THER, V8, P282, DOI 10.1583/1545-1550(2001)008<0282:ATDIVU>2.0.CO
[3]  
2
[4]   The use of transducer-tipped ultrasound catheter for recanalization of thrombotic arterial occlusions [J].
Atar, S ;
Luo, H ;
Birnbaum, Y ;
Hansmann, D ;
Siegel, RJ .
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 2001, 18 (03) :233-237
[5]  
Atar S, 1999, Eur J Ultrasound, V9, P39, DOI 10.1016/S0929-8266(99)00007-5
[6]   Noninvasive in vivo clot dissolution without a thrombolytic drug - Recanalization of thrombosed iliofemoral arteries by transcutaneous ultrasound combined with intravenous infusion of microbubbles [J].
Birnbaum, Y ;
Luo, H ;
Nagai, T ;
Fishbein, MC ;
Peterson, TM ;
Li, SP ;
Kricsfeld, D ;
Porter, TR ;
Siegel, RJ .
CIRCULATION, 1998, 97 (02) :130-134
[7]  
Cohen MG, 2002, EUR HEART J, V23, P724
[8]   EFFECTS OF ULTRASOUND ENERGY ON TOTAL PERIPHERAL ARTERY OCCLUSIONS - INITIAL ANGIOGRAPHIC AND ANGIOSCOPIC RESULTS [J].
DROBINSKI, G ;
BRISSET, D ;
PHILIPPE, F ;
KREMER, D ;
LAURIAN, C ;
MONTALESCOT, G ;
THOMAS, D .
JOURNAL OF INTERVENTIONAL CARDIOLOGY, 1993, 6 (02) :157-163
[9]   ENHANCEMENT OF FIBRINOLYSIS INVITRO BY ULTRASOUND [J].
FRANCIS, CW ;
ONUNDARSON, PT ;
CARSTENSEN, EL ;
BLINC, A ;
MELTZER, RS ;
SCHWARZ, K ;
MARDER, VJ .
JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (05) :2063-2068
[10]   CORONARY ULTRASOUND THROMBOLYSIS IN A PATIENT WITH ACUTE MYOCARDIAL-INFARCTION [J].
HAMM, CW ;
REIMERS, J ;
KOSTER, R ;
TERRES, W ;
STIEL, GM ;
KOSCHYK, DH ;
KUCK, KH ;
SIEGEL, RJ .
LANCET, 1994, 343 (8897) :605-606