Radical-polar crossover domino reactions involving organozinc and mixed organocopper/organozinc reagents

被引：41

作者：

Denes, Fabrice ^{[1
]}

Cutri, Sabrina ^{[1
]}

Perez-Luna, Alejandro ^{[1
]}

Chemla, Fabrice ^{[1
]}

机构：

[1] Univ Paris 06, Chim Organ Lab, UMR 7611, CNRS,Inst Chim Mol, F-75252 Paris 05, France

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2006年 / 12卷 / 25期

关键词：

copper; domino reactions; Michael addition; radical reactions; zinc;

D O I：

10.1002/chem.200600334

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A domino process involving Michael addition and carbocyclization has been developed starting from beta-N-allylamino enoates and various organometallic reagents (organozinc halides, diorganozinc reagents, and copper/zinc mixed species). In all cases the mechanism of this domino reaction has been evidenced to involve a radical-polar crossover mechanism.

引用

页码：6506 / 6513

页数：8

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