Simultaneous intensity, birefringence, and flow measurements with high-speed fiber-based optical coherence tomography

被引:74
作者
Pierce, MC [1 ]
Park, BH [1 ]
Cense, B [1 ]
de Boer, JF [1 ]
机构
[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Wellman Labs Photomed, Boston, MA 02114 USA
关键词
D O I
10.1364/OL.27.001534
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We demonstrate that tissue structure, birefringence, and blood flow can be imaged simultaneously by use of techniques of polarization-sensitive optical coherence tomography and phase-resolved optical Doppler tomography. An efficient data-acquisition procedure is implemented that optimizes the concurrent processing and display of all three image types. Images of in vivo human skin acquired with a high-speed fiber-based system are presented. (C) 2002 Optical Society of America.
引用
收藏
页码:1534 / 1536
页数:3
相关论文
共 18 条
[1]   Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography [J].
Bouma, BE ;
Tearney, GJ .
OPTICS LETTERS, 1999, 24 (08) :531-533
[2]   Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography [J].
Chen, ZP ;
Milner, TE ;
Srinivas, S ;
Wang, XJ ;
Malekafzali, A ;
vanGemert, MJC ;
Nelson, JS .
OPTICS LETTERS, 1997, 22 (14) :1119-1121
[3]   Determination of the depth-resolved Stokes parameters of light backscattered from turbid media by use of polarization-sensitive optical coherence tomography [J].
de Boer, JF ;
Milner, TE ;
Nelson, JS .
OPTICS LETTERS, 1999, 24 (05) :300-302
[4]   Stable carrier generation and phase-resolved digital data processing in optical coherence tomography [J].
de Boer, JF ;
Saxer, CE ;
Nelson, JS .
APPLIED OPTICS, 2001, 40 (31) :5787-5790
[5]   Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography [J].
deBoer, JF ;
Milner, TE ;
vanGemert, MJC ;
Nelson, JS .
OPTICS LETTERS, 1997, 22 (12) :934-936
[6]   In vivo ultrahigh-resolution optical coherence tomography [J].
Drexler, W ;
Morgner, U ;
Kärtner, FX ;
Pitris, C ;
Boppart, SA ;
Li, XD ;
Ippen, EP ;
Fujimoto, JG .
OPTICS LETTERS, 1999, 24 (17) :1221-1223
[7]   OPTICAL COHERENCE TOMOGRAPHY [J].
HUANG, D ;
SWANSON, EA ;
LIN, CP ;
SCHUMAN, JS ;
STINSON, WG ;
CHANG, W ;
HEE, MR ;
FLOTTE, T ;
GREGORY, K ;
PULIAFITO, CA ;
FUJIMOTO, JG .
SCIENCE, 1991, 254 (5035) :1178-1181
[8]   In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomograghy [J].
Izatt, JA ;
Kulkami, MD ;
Yazdanfar, S ;
Barton, JK ;
Welch, AJ .
OPTICS LETTERS, 1997, 22 (18) :1439-1441
[9]   Two-dimensional depth-resolved Mueller matrix of biological tissue measured with double-beam polarization-sensitive optical coherence tomography [J].
Jiao, SL ;
Wang, LHV .
OPTICS LETTERS, 2002, 27 (02) :101-103
[10]   In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography [J].
Park, BH ;
Saxer, C ;
Srinivas, SM ;
Nelson, JS ;
de Boer, JF .
JOURNAL OF BIOMEDICAL OPTICS, 2001, 6 (04) :474-479