Comparison of the Gyro C1E3 and BioMedicus centrifugal pump performances during cardiopulmonary bypass

被引:3
作者
Nakazawa, T [1 ]
Takami, Y [1 ]
Makinouchi, K [1 ]
Gay, J [1 ]
Taylor, D [1 ]
Ueyama, K [1 ]
Ohashi, Y [1 ]
Kawahito, K [1 ]
Tayama, E [1 ]
Glueck, J [1 ]
Nose, Y [1 ]
机构
[1] BAYLOR COLL MED,DEPT SURG,HOUSTON,TX 77030
关键词
C1ES; centrifugal pump; pivot bearing system; cardiopulmonary bypass pump;
D O I
10.1111/j.1525-1594.1997.tb03742.x
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The compact eccentric inlet port (C1E3) centrifugal blood pump was developed as a cardiopulmonary bypass (CPB) pump. The C1E3 pump incorporated a seal-less design with a blood stagnation free structure. The pump impeller was magnetically coupled to the driver magnet in a seal-less manner. To develop an atraumatic and antithrombogenic centrifugal pump without a shaft seal junction, a double pivot bearing system was introduced. Recently, a mass production model of the C1E3 was fabricated and evaluated. The ratio of the normalized index of hemolysis (NIH) of the C1E3 was 0.007 g/100 L, in comparison to the NIH of the BP-80, 0.018 g/100 L, each in a CPB condition of 5 L/min against 325 mm Hg. Both pumps were compared in identical in vitro circuits. To further evaluate the pumps during cardiopulmonary bypass for reliability and function, 6 h of CPB was performed on each of 8 bovines using either the C1E3 or BP-80 centrifugal pump. The BP-80 and C1E3 provided pump flows of 50-60 ml/kg/min without incident. The hemodynamics were stable, and the hematology and biochemistry data were within normal ranges. There were no statistically significant differences between the 2 groups. Concerning the plasma free hemoglobin values, a mass production model of the C1E3 pump had the same hemolysis levels as the BP-80. Our preliminary studies reveal that the C1E3 pump is reliable. Also, the C1E3 will satisfy clinical requirements as a cardiopulmonary bypass pump.
引用
收藏
页码:782 / 785
页数:4
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