Electrochemical biosensors - principles and applications

被引:213
作者
Pohanka, Miroslav [1 ]
Skladai, Petr [2 ,3 ]
机构
[1] Univ Def, Ctr Adv Studies, Fac Mil Hlth Sci, Hradec Kralove, Czech Republic
[2] Masaryk Univ, Dept Biochem, Brno, Czech Republic
[3] Masaryk Univ, Natl Ctr Biomol Res, Brno, Czech Republic
关键词
enzyme electrode; immunosensor; potentiometric; amperometric; impedimetric transducer;
D O I
10.32725/jab.2008.008
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The first scientifically proposed as well as successfully commercialized biosensors were those based on electrochemical sensors for multiple analytes. Electrochemical biosensors have been studied for a long time. Currently, transducers based on semiconductors and screen printed electrodes represent a typical platform for the construction of biosensors. Enzymes or enzyme labeled antibodies are the most common biorecognition components of biosensors. The principles of, and the most typical applications for electrochemical biosensors are described in this review. The relevant systems are divided into three types according to the operating principle governing their method of measurement: potentiometric, amperometric and impedimetric transducers, and the representative devices are described for each group. Some of the most typical assays are also mentioned in the text.
引用
收藏
页码:57 / 64
页数:8
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