Transcription modulation of Salmonella enterica serovar typhimurium promoters by sub-MIC levels of rifampin

被引：46

作者：

Yim, Grace

de la Cruz, Fernando

Spiegelman, George B.

Davies, Julian

机构：

[1] Univ British Columbia, Dept Microbiol & Immunol, Inst Life Sci, Vancouver, BC V6T 1Z3, Canada

[2] Univ Cantabria, Dept Biol Mol, Santander 39011, Spain

来源：

JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 22期

关键词：

D O I：

10.1128/JB.00791-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Promoter-lux fusions that showed rifampin-modulated transcription were identified from a Salmonella enterica serovar Typhimurium 14028 reporter library. The transformation of a subset of fusions into mutants that lacked one of six global regulatory proteins or were rifampin resistant showed that transcription modulation was independent of the global regulators, promoter specific, and dependent on the interaction of rifampin with RNA polymerase.

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收藏

页码：7988 / 7991

页数：4

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