Briaexcavatolides A-J, new diterpenes from the gorgonian Briareum excavatum

被引：41

作者：

Sheu, JH ^{[1
]}

Sung, PJ

Su, JH

Liu, HY

Duh, CY

Chiang, MY

机构：

[1] Natl Sun Yat Sen Univ, Dept Marine Resources, Kaohsiung 804, Taiwan

[2] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan

来源：

TETRAHEDRON | 1999年 / 55卷 / 51期

关键词：

Briareum excavatum; briarane diterpene; briaexcavatolide; gorgonian; cytotoxicity;

D O I：

10.1016/S0040-4020(99)00931-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ten new briarane-type diterpenes have been isolated from the gorgonian octocoral Briareum excavatum. The structures of these secondary metabolites, named briaexcavatolides A-J (1-10), were established by spectroscopic and chemical methods. The structure, including the relative configuration of briaexcavatolide B (2), was further confirmed by a single-crystal X-ray structure analysis. Cytotoxicity of these compounds toward various cancer cell lines also is described. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：14555 / 14564

页数：10

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