Characteristics of patients with Crimean-Congo hemorrhagic fever in a recent outbreak in Turkey and impact of oral ribavirin therapy

被引：238

作者：

Ergönül, Ö ^{[1
]}

Çelikbas, A ^{[1
]}

Dokuzoguz, B ^{[1
]}

Eren, S ^{[1
]}

Baykam, N ^{[1
]}

Esener, H ^{[1
]}

机构：

[1] Ankara Numune Educ & Res Hosp, Infect Dis & Clin Microbiol Dept, Ankara, Turkey

来源：

CLINICAL INFECTIOUS DISEASES | 2004年 / 39卷 / 02期

关键词：

D O I：

10.1086/422000

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe the epidemiological, clinical, and laboratory findings and the role of ribavirin therapy for 35 patients who received a diagnosis of Crimean-Congo hemorrhagic fever (CCHF). All patients had immunoglobulin M antibodies and/or PCR results positive for CCHF virus in blood or tissue specimens. Eighty-six percent of the patients were considered to have severe cases of CCHF. The overall case-fatality rate was 2.8%. Eight patients were given ribavirin, and all 8 survived. We suggest using ribavirin to treat patients with CCHF, particularly those with severe cases.

引用

页码：284 / 287

页数：4

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