New extraction procedure to improve the determination of quinolones in poultry muscle by liquid chromatography with ultraviolet and mass spectrometric detection

被引：47

作者：

Bailac, S. ^{[1
]}

Barron, D. ^{[1
]}

Barbosa, J. ^{[1
]}

机构：

[1] Univ Barcelona, Dept Analyt Chem, E-08028 Barcelona, Spain

来源：

ANALYTICA CHIMICA ACTA | 2006年 / 580卷 / 02期

关键词：

liquid chromatography; mass spectrometry; ultraviolet detection; chicken tissues and quinolones;

D O I：

10.1016/j.aca.2006.07.064

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The present article aims to develop a new extraction procedure to improve the determination of quinolones in chicken muscle. This new determination method was validated using liquid chromatography-ultraviolet detection (LC-UV) and liquid chromatography-mass spectrometry detection (LC-MS), which has special bearing on stability studies. The results obtained by using the method were compared with the results obtained with a previous methodology. The new extraction procedure presents a sensitivity low enough to determine concentration of these drugs below the permissible maximum residue limits (MRL) in chicken muscle and is less time consuming than the previous methodology. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：163 / 169

页数：7

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