Projection structure of a gap junction membrane channel at 7 angstrom resolution

被引：100

作者：

Unger, VM

Kumar, NM

Gilula, NB

Yeager, M

机构：

[1] SCRIPPS RES INST, DEPT CELL BIOL, LA JOLLA, CA 92037 USA

[2] SCRIPPS CLIN, DIV CARDIOVASC DIS, LA JOLLA, CA 92037 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 01期

关键词：

D O I：

10.1038/nsb0197-39

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Electron cryo-microscopy and image analysis of frozen-hydrated, two-dimensional crystals of gap junction membrane channels formed by recombinant alpha(1) connexin (Cx43) reveal a ring of transmembrane alpha-helices that lines the aqueous pore and a second ring of alpha-helices in close contact with the membrane lipids.

引用

收藏

页码：39 / 43

页数：5

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