Electrochemical DNA Hybridization Biosensors

被引：5

作者：

Gooding, JJ ^{[1
]}

机构：

[1] Univ New S Wales, Sch Chem Sci, Sydney, NSW 2052, Australia

来源：

ELECTROANALYSIS | 2002年 / 14卷 / 17期

关键词：

electrochemical DNA hybridization biosensors; DNA recognition interface; transduction of DNA hybridization; redox labels; indicator-free detection;

D O I：

10.1002/1521-4109(200209)14:17<1149::AID-ELAN1149>3.0.CO;2-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The many different approaches in which electrochemical methods are used to detect DNA hybridization, as the basis of a DNA biosensors, are reviewed. Transduction of the hybridization event can be divided into two broad classes, approaches where a redox active species is used as a label and those where changes in the DNA interface are monitored electrochemically without the use of any labels. Important criteria in fabricating the DNA recognition interface on an electrode and future challenges are also discussed.

引用

页码：1149 / 1156

页数：8

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