blaCTX-M Genes in Escherichia coli Strains from Croatian Hospitals Are Located in New (blaCTX-M-3a) and Widely Spread (blaCTX-M-3a and blaCTX-M-15) Genetic Structures

被引：57

作者：

Literacka, Elzbieta ^{[1
]}

Bedenic, Branka ^{[2
,3
]}

Baraniak, Anna ^{[1
]}

Fiett, Janusz ^{[1
]}

Tonkic, Marija ^{[4
]}

Jajic-Bencic, Ines ^{[5
]}

Gniadkowski, Marek ^{[1
]}

机构：

[1] Natl Med Inst, PL-00725 Warsaw, Poland

[2] Univ Zagreb, Sch Med, Zagreb 41001, Croatia

[3] Univ Zagreb, Clin Hosp Ctr, Zagreb, Croatia

[4] Univ Hosp, Split, Croatia

[5] Univ Zagreb, Sisters Mercy Univ Hosp, Zagreb, Croatia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 04期

关键词：

SPECTRUM BETA-LACTAMASES; COMPLETE NUCLEOTIDE-SEQUENCE; CTX-M; AMINOGLYCOSIDE RESISTANCE; ENTEROBACTERIACEAE; PLASMID; CTX-M-3; DISSEMINATION; IDENTIFICATION; MOBILIZATION;

D O I：

10.1128/AAC.01431-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

CTX-M-producing Escherichia coli isolates from three Croatian hospitals were analyzed. All bla(CTX-M-15) genes and one bla(CTX-M-3a) gene resided in widely spread ISEcp1 transposition modules, but other bla(CTX-M-3a) genes were in a new configuration with two IS26 copies, indicating a new event of gene mobilization from a Kluyvera ascorbata genome. The study confirmed the role of the E. coli ST131 clonal group with IncFII-type plasmids in the spread of bla(CTX-M-15) and of IncL/M pCTX-M3-type plasmids in the dissemination of bla(CTX-M-3a).

引用

收藏

页码：1630 / 1635

页数：6

相关论文

共 41 条

[11] Rapid and simple determination of the Escherichia coli phylogenetic group [J].

Clermont, O ;

Bonacorsi, S ;

Bingen, E .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2000, 66 (10) :4555-4558

[12]

Clinical and Laboratory Standards Institute, 2007, M100S17 CLSI

[13] Dissemination of clonally related Escherichia coli strains expressing extended-spectrum β-lactamase CTX-M-15 [J].

Coque, Teresa M. ;

Novais, Angela ;

Carattoli, Alessandra ;

Poirel, Laurent ;

Pitout, Johann ;

Peixe, Luisa ;

Baquero, Fernando ;

Canton, Rafael ;

Nordmannj, Patrice .

EMERGING INFECTIOUS DISEASES, 2008, 14 (02) :195-200

[14] DNA sequence analysis of the genetic environment of various blaCTX-M genes [J].

Eckert, C ;

Gautier, V ;

Arlet, G .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 57 (01) :14-23

[15] Comparative genomics of multidrug resistance in Acinetobacter baumannii [J].

Fournier, Pierre-Edouard ;

Vallenet, David ;

Barbe, Valerie ;

Audic, Stephane ;

Ogata, Hiroyuki ;

Poirel, Laurent ;

Richet, Herve ;

Robert, Catherine ;

Mangenot, Sophie ;

Abergel, Chantal ;

Nordmann, Patrice ;

Weissenbach, Jean ;

Raoult, Didier ;

Claverie, Jean-Michel .

PLOS GENETICS, 2006, 2 (01) :62-72

[16] Cefotaxime-resistant Enterobacteriaceae isolates from a hospital in Warsaw, Poland:: Identification of a new CTX-M-3 cefotaxime-hydrolyzing β-lactamase that is closely related to the CTX-M-1/MEN-1 enzyme [J].

Gniadkowski, M ;

Schneider, I ;

Palucha, A ;

Jungwirth, R ;

Mikiewicz, B ;

Bauernfeind, A .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (04) :827-832

[17] Complete nucleotide sequence of the pCTX-M3 plasmid and its involvement in spread of the extended-spectrum β-lactamase gene blaCTX-M-3 [J].

Golebiewski, M. ;

Kern-Zdanowicz, I. ;

Zienkiewicz, M. ;

Adamczyk, M. ;

Zylinska, J. ;

Baraniak, A. ;

Gniadkowski, M. ;

Bardowski, J. ;

Ceglowski, P. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (11) :3789-3795

[18] Replicon typing of Plasmids carrying CTX-M or CMY β-lactamases circulating among Salmonella and Escherichia coli isolates [J].

Hopkins, Katie L. ;

Liebana, Ernesto ;

Villa, Laura ;

Batchelor, Miranda ;

Threlfall, E. John ;

Carattoli, Alessandra .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (09) :3203-3206

[19]

JARLIER V, 1988, REV INFECT DIS, V10, P867

[20]

Karim A, 2001, FEMS MICROBIOL LETT, V201, P237, DOI 10.1111/j.1574-6968.2001.tb10762.x

← 1 2 3 4 5 →