The first total synthesis and absolute stereochemistry of plakortone G from the Jamaican sponge Plakortis sp.

被引：21

作者：

Kowashi, S ^{[1
]}

Ogamino, T ^{[1
]}

Kamei, J ^{[1
]}

Ishikawa, Y ^{[1
]}

Nishiyama, S ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 22期

关键词：

Plakortis sp; alpha; beta-unsaturated gamma-lactone; absolute stereochemistry; plakortones;

D O I：

10.1016/j.tetlet.2004.03.169

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Total synthesis of plakortone G (1), a secondary metabolite of the Jamaican sponge Plakortis sp., was successfully achieved. The absolute configuration of this molecule was determined by comparison of the synthetic diastereomers with reported data to possess the (4R,8R)-configuration 14. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：4393 / 4396

页数：4

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