ANOMALOUS ENANTIOSELECTIVITY IN THE SHARPLESS CATALYTIC ASYMMETRIC DIHYDROXYLATION REACTION OF 1,1-DISUBSTITUTED ALLYL ALCOHOL DERIVATIVES

被引：46

作者：

HALE, KJ

MANAVIAZAR, S

PEAK, SA

机构：

[1] The Christopher Ingold Laboratories, Department of Chemistry, University College London, London, WC1H 0AJ England

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 03期

关键词：

D O I：

10.1016/0040-4039(94)85071-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Sharpless asymmetric dihydroxylation (AD) reaction has been examined on a number of 1,1-disubstituted allyl alcohol derivatives. In the majority of substrates studied, the product diols had ee's in the 9-11% range and had absolute stereochemistry opposite to that predicted using the Sharpless steric model.

引用

页码：425 / 428

页数：4

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