EcoCyc: Encyclopedia of Escherichia coli genes and metabolism

被引：32

作者：

Karp, PD ^{[1
]}

Riley, M ^{[1
]}

Paley, SM ^{[1
]}

PellegriniToole, A ^{[1
]}

Krummenacker, M ^{[1
]}

机构：

[1] MARINE BIOL LAB, WOODS HOLE, MA 02543 USA

来源：

NUCLEIC ACIDS RESEARCH | 1997年 / 25卷 / 01期

关键词：

D O I：

10.1093/nar/25.1.43

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Encyclopedia of Genes and Metabolism (EcoCyc) is a database that combines information about the genome and the intermediary metabolism of Escherichia coli, It describes 2970 genes of E.coli, 547 enzymes encoded by these genes, 702 metabolic reactions that occur in E.coli and the organization of these reactions into 107 metabolic pathways. The EcoCyc graphical user interface allows scientists to query and explore the EcoCyc database using visualization tools such as genomic-map browsers and automatic layouts of metabolic pathways, EcoCyc spans the space from sequence to function to allow scientists to investigate an unusually broad range of questions, EcoCyc can be thought of as both an electronic review article because of its copious references to the primary literature, and as an in silicio model of E.coli metabolism that can be probed and analyzed through computational means.

引用

页码：43 / 50

页数：8

共 21 条

[11] KARP PD, 1992, COMPUT APPL BIOSCI, V8, P347
[12] EcoCyc: An encyclopedia of Escherichia coli genes and metabolism
Karp, PD
Riley, M
Paley, SM
PelligriniToole, A
[J]. NUCLEIC ACIDS RESEARCH, 1996, 24 (01) : 32 - 39
[13] KARP PD, 1994, LISP SYMBOLIC COMPUT, V7, P245
[14] KARP PD, 521 SRI ART INT CTR
[15] KARP PD, 1996, P 4 INT C INT SYST M, P116
[16] KARP PD, 1994, P 3 INT C BIOINF GEN
[17] Paley SM, 1996, GENE, V172, pGC43, DOI 10.1016/0378-1119(96)00269-7
[18] FUNCTIONS OF THE GENE-PRODUCTS OF ESCHERICHIA-COLI
RILEY, M
[J]. MICROBIOLOGICAL REVIEWS, 1993, 57 (04) : 862 - 952
[19] The metabolic pathway collection from EMP: The enzymes and metabolic pathways database
Selkov, E
Basmanova, S
Gaasterland, T
Goryanin, I
Gretchkin, Y
Maltsev, N
Nenashev, V
Overbeek, R
Panyushkina, E
Pronevitch, L
Selkov, E
Yunis, I
[J]. NUCLEIC ACIDS RESEARCH, 1996, 24 (01) : 26 - 28
[20] Walker G.C., 1996, Escherichia coli and Salmonella

← 1 2 3 →