Harnessing actin dynamics for clathrin-mediated endocytosis

被引：571

作者：

Kaksonen, Marko ^{[1
]}

Toret, Christopher P. ^{[1
]}

Drubin, David G. ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Cell & Mol Biol, Berkeley, CA 94720 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2006年 / 7卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrm1940

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Actin polymerization often occurs at the plasma membrane to drive the protrusion of lamellipodia and filopodia at the leading edge of migrating cells. A role for actin polymerization in another cellular process that involves the reshaping of the plasma membrane - namely endocytosis - has recently been established. Live-cell imaging studies are shedding light on the order and timing of the molecular events and mechanisms of actin function during endocytosis.

引用

页码：404 / 414

页数：11

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