A photoswitchable miniprotein based on the sequence of avian pancreatic polypeptide

被引：25

作者：

Jurt, Simon

Aemissegger, Andreas

Guentert, Peter

Zerbe, Oliver ^{[1
]}

Hilvert, Donald

机构：

[1] Univ Zurich, Inst Organ Chem, CH-8057 Zurich, Switzerland

[2] ETH, Organ Chem Lab, CH-8093 Zurich, Switzerland

[3] RIKEN, Genom Sci Ctr, Yokohama, Kanagawa 2300045, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 38期

关键词：

azobenzene; peptides; photochromic compounds; protein folding; tertiary structures;

D O I：

10.1002/anie.200602084

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

(Figure Presented) Flip a switch: A peptide capable of adopting different conformations is constructed upon insertion of an azobenzene linker into the polypeptide backbone. A simple transformation (irradiation or heating) can be used to switch from one form to the other. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：6297 / 6300

页数：4

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