Pfam:: clans, web tools and services

被引:1814
作者
Finn, Robert D.
Mistry, Jaina
Schuster-Bockler, Benjamin
Griffiths-Jones, Sam
Hollich, Volker
Lassmann, Timo
Moxon, Simon
Marshall, Mhairi
Khanna, Ajay
Durbin, Richard
Eddy, Sean R.
Sonnhammer, Erik L. L.
Bateman, Alex
机构
[1] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England
[2] Karolinska Inst, Ctr Genom & Bioinformat, S-17177 Stockholm, Sweden
[3] Washington Univ, Sch Med, Howard Hughes Med Inst, Dept Genet, St Louis, MO 63110 USA
基金
英国医学研究理事会;
关键词
D O I
10.1093/nar/gkj149
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pfam is a database of protein families that currently contains 7973 entries (release 18.0). A recent development in Pfam has enabled the grouping of related families into clans. Pfam clans are described in detail, together with the new associated web pages. Improvements to the range of Pfam web tools and the first set of Pfam web services that allow programmatic access to the database and associated tools are also presented. Pfam is available on the web in the UK (http://www.sanger.ac.uk/Software/Pfam/),the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http://pfam.cgb.ki.se/).
引用
收藏
页码:D247 / D251
页数:5
相关论文
共 16 条
  • [1] SCOP database in 2004: refinements integrate structure and sequence family data
    Andreeva, A
    Howorth, D
    Brenner, SE
    Hubbard, TJP
    Chothia, C
    Murzin, AG
    [J]. NUCLEIC ACIDS RESEARCH, 2004, 32 : D226 - D229
  • [2] The universal protein resource (UniProt)
    Bairoch, A
    Apweiler, R
    Wu, CH
    Barker, WC
    Boeckmann, B
    Ferro, S
    Gasteiger, E
    Huang, HZ
    Lopez, R
    Magrane, M
    Martin, MJ
    Natale, DA
    O'Donovan, C
    Redaschi, N
    Yeh, LSL
    [J]. NUCLEIC ACIDS RESEARCH, 2005, 33 : D154 - D159
  • [3] Bateman A, 2004, NUCLEIC ACIDS RES, V32, pD138, DOI [10.1093/nar/gkp985, 10.1093/nar/gkr1065, 10.1093/nar/gkh121]
  • [4] MUSCLE: multiple sequence alignment with high accuracy and high throughput
    Edgar, RC
    [J]. NUCLEIC ACIDS RESEARCH, 2004, 32 (05) : 1792 - 1797
  • [5] iPfam:: visualization of protein-protein interactions in PDB at domain and amino acid resolutions
    Finn, RD
    Marshall, M
    Bateman, A
    [J]. BIOINFORMATICS, 2005, 21 (03) : 410 - 412
  • [6] Recent improvements to the PROSITE database
    Hulo, N
    Sigrist, CJA
    Le Saux, V
    Langendijk-Genevaux, PS
    Bordoli, L
    Gattiker, A
    De Castro, E
    Bucher, P
    Bairoch, A
    [J]. NUCLEIC ACIDS RESEARCH, 2004, 32 : D134 - D137
  • [7] Recent improvements to the SMART domain-based sequence annotation resource
    Letunic, I
    Goodstadt, L
    Dickens, NJ
    Doerks, T
    Schultz, J
    Mott, R
    Ciccarelli, F
    Copley, RR
    Ponting, CP
    Bork, P
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 242 - 244
  • [8] SMART 4.0: towards genomic data integration
    Letunic, I
    Copley, RR
    Schmidt, S
    Ciccarelli, FD
    Doerks, T
    Schultz, J
    Ponting, CP
    Bork, P
    [J]. NUCLEIC ACIDS RESEARCH, 2004, 32 : D142 - D144
  • [9] The SUPERFAMILY database in 2004: additions and improvements
    Madera, M
    Vogel, C
    Kummerfeld, SK
    Chothia, C
    Gough, J
    [J]. NUCLEIC ACIDS RESEARCH, 2004, 32 : D235 - D239
  • [10] SUPFAM: A database of sequence superfamilies of protein domains
    Pandit, SB
    Bhadra, R
    Gowri, VS
    Balaji, S
    Anand, B
    Srinivasan, N
    [J]. BMC BIOINFORMATICS, 2004, 5 (1)