Inactivation of human type A and B influenza viruses by tea-seed saponins

被引：25

作者：

Hayashi, K

Sagesaka, YM

Suzuki, T

Suzuki, Y

机构：

[1] Ito En Ltd, Cent Res Inst, Shizuoka 4210516, Japan

[2] Univ Shizuoka, Sch Pharmaceut Sci, Dept Biochem, Shizuoka 4228526, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2000年 / 64卷 / 01期

关键词：

saponin; tea; influenza virus; inactivation;

D O I：

10.1271/bbb.64.184

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effects of a mixture of tea-seed saponins obtained from the seeds of Camellia sinensis var. sinensis on human influenza viruses types A and B were investigated. At the concentrations: of 60, 80, and 100 mu g/ml, respectively, the mixture inactivated viruses A/Memphis/1/71 (H3N2), B/Lee/40, and A/PR/8/34 (H1N1) almost completely. The mixture also inactivated type A virus A/PR/8/34 after inoculation at concentrations of 1-30 mu g/ml dose-dependents.

引用

页码：184 / 186

页数：3

共 13 条

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Akagi M, 1997, BIOL PHARM BULL, V20, P565, DOI 10.1248/bpb.20.565

[2]

HASHIZUME AKITO, 1966, NIPPON NOGEIKAGAKU KAISHI, V40, P8

[3] THE MOLECULAR-BASIS OF THE SPECIFIC ANTI-INFLUENZA ACTION OF AMANTADINE [J].