Corticotropin-releasing hormone receptors

被引：46

作者：

Hillhouse, EW ^{[1
]}

Randeva, H ^{[1
]}

Ladds, G ^{[1
]}

Grammatopoulos, D ^{[1
]}

机构：

[1] Univ Warwick, Dept Sci Biol, Mol Med Res Ctr, Coventry CV4 7AL, W Midlands, England

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2002年 / 30卷

关键词：

CRH; G-protein-coupled receptors; receptor isoforms; urocortin;

D O I：

10.1042/bst0300428

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Corticotropin-releasing hormone (CRH) and related peptides (urocortins, sauvagine, urotensin) play a central role in the co-ordination of autonomic, behavioural, cardiovascular, immune and endocrine responses to stressful stimuli. Their actions are mediated through activation of two types of G-protein-coupled receptors encoded by separate genes. In this review we focus on the diverse structural and functional characteristics of the family of CRH-like peptides and their receptors.

引用

页码：428 / 432

页数：5

共 49 条

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