Magnetic-fluorescent nanocomposites for biomedical multitasking

被引：63

作者：

Corr, Serena A.

O' Byrne, Aisling

Gun'ko, Yurii K. ^{[1
]}

Ghosh, Swapankumar

Brougham, Dermot F.

Mitchell, Siobhan

Volkov, Yuri

Prina-Mello, Adriele

机构：

[1] Univ Dublin Trinity Coll, Sch Chem, Dublin 2, Ireland

[2] Dublin City Univ, Sch Chem Sci, Natl Inst Cellular Biotechnol, Dublin 9, Ireland

[3] Univ Dublin Trinity Coll, Dept Clin Med, Dublin 2, Ireland

[4] Univ Dublin Trinity Coll, Ctr Res Adapt Nanostruct & Nanodevices, Dublin 2, Ireland

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 43期

关键词：

D O I：

10.1039/b610746j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluorescent magnetite nanocomposites based on magnetic nanoparticles, a polyhedral octaaminopropylsilsesquioxane and a porphyrin derivative have been prepared. The intracellular uptake of the nanocomposites by macrophage and bone osteoblast cells, and their potential as MRI contrast agents, has been demonstrated.

引用

收藏

页码：4474 / 4476

页数：3

相关论文

共 22 条

[1] Magnetic ion-exchange nano- and microparticles for medical, biochemical and molecular biological applications [J].

Bergemann, C ;

Müller-Schulte, D ;

Oster, J ;

à Brassard, L ;

Lübbe, AS .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 1999, 194 (1-3) :45-52

[2] Fluorescence-modified superparamagnetic nanoparticles:: Intracellular uptake and use in cellular imaging [J].

Bertorelle, Franck ;

Wilhelm, Claire ;

Roger, Jacky ;

Gazeau, Florence ;

Menager, Christine ;

Cabuil, Valerie .

LANGMUIR, 2006, 22 (12) :5385-5391

[3] PHOTOSENSITIZERS OF THE PORPHYRIN AND PHTHALOCYANINE SERIES FOR PHOTODYNAMIC THERAPY [J].

BONNETT, R .

CHEMICAL SOCIETY REVIEWS, 1995, 24 (01) :19-33

[4] Magnetic nanoparticle assemblies on denatured DNA show unusual magnetic relaxivity and potential applications for MRI [J].

Byrne, SJ ;

Corr, SA ;

Gun'ko, YK ;

Kelly, JM ;

Brougham, DF ;

Ghosh, S .

CHEMICAL COMMUNICATIONS, 2004, (22) :2560-2561

[5] Mediators of peripheral blood neutrophilia induced by photodynamic therapy of solid tumors [J].

Cecic, I ;

Korbelik, M .

CANCER LETTERS, 2002, 183 (01) :43-51

[6]

Feher FJ, 1999, J CHEM SOC DALTON, P1491

[7] Recognition of protonated aliphatic α,ω-diamines by coproporphyrin I tetraanion in water [J].

Flores-Villalobos, A ;

Morales-Rojas, H ;

Escalante-Tovar, S ;

Yatsimirsky, AK .

JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2002, 15 (02) :83-93

[8] Synthesis and cellular uptake of porphyrin decorated iron oxide nanoparticles - a potential candidate for bimodal anticancer therapy [J].

Gu, HW ;

Xu, KM ;

Yang, ZM ;

Chang, CK ;

Xu, B .

CHEMICAL COMMUNICATIONS, 2005, (34) :4270-4272

[9] Magnetic fluid hyperthermia (MFH):: Cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles [J].

Jordan, A ;

Scholz, R ;

Wust, P ;

Fähling, H ;

Felix, R .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 1999, 201 :413-419

[10] Presentation of a new magnetic field therapy system for the treatment of human solid tumors with magnetic fluid hyperthermia [J].

Jordan, A ;

Scholz, R ;

Maier-Hauff, K ;

Johannsen, M ;

Wust, P ;

Nadobny, J ;

Schirra, H ;

Schmidt, H ;

Deger, S ;

Loening, S ;

Lanksch, W ;

Felix, R .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2001, 225 (1-2) :118-126