Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases

被引:16
作者
Barlan, I [1 ]
Bahceciler, NN
Akdis, M
Akdis, CA
机构
[1] Marmara Univ Hosp, Div Pediat Allergy & Immunol, TR-81190 Istanbul, Turkey
[2] Swiss Inst Allergy & Asthma Res, CH-7270 Davos, Switzerland
关键词
D O I
10.1016/j.iac.2006.02.002
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Based on the hygiene hypothesis association between atopy and bacillus Calmette-Guerin (BCG), purified protein derivative skin test reaction, mycobacterial disease, and environmental mycobacteria are summarized. The role of mycobacterial species in the activation of the innate immune response through Toll-like receptors is mentioned. The implications and perspectives of BCG as a potential therapeutic adjuvant in atopic disease are discussed.
引用
收藏
页码:365 / +
页数:14
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