Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases

被引：16

作者：

Barlan, I ^{[1
]}

Bahceciler, NN

Akdis, M

Akdis, CA

机构：

[1] Marmara Univ Hosp, Div Pediat Allergy & Immunol, TR-81190 Istanbul, Turkey

[2] Swiss Inst Allergy & Asthma Res, CH-7270 Davos, Switzerland

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2006年 / 26卷 / 02期

关键词：

D O I：

10.1016/j.iac.2006.02.002

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Based on the hygiene hypothesis association between atopy and bacillus Calmette-Guerin (BCG), purified protein derivative skin test reaction, mycobacterial disease, and environmental mycobacteria are summarized. The role of mycobacterial species in the activation of the innate immune response through Toll-like receptors is mentioned. The implications and perspectives of BCG as a potential therapeutic adjuvant in atopic disease are discussed.

引用

页码：365 / +

页数：14

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