Facile synthesis of responsive nanoparticles with reversible, tunable and rapid thermal transitions from biocompatible constituents

被引：26

作者：

Abulateefeh, Samer R.

Saeed, Aram O.

Aylott, Jonathan W.

Chan, Weng C. ^{[1
]}

Garnett, Martin C.

Saunders, Brian R. ^{[2
]}

Alexander, Cameron ^{[1
]}

机构：

[1] Univ Nottingham, Sch Pharm, Ctr Biomol Sci, Nottingham NG7 2RD, England

[2] Univ Manchester, Sch Mat, Manchester M1 7HS, Lancs, England

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 40期

基金：

英国工程与自然科学研究理事会;

关键词：

POLYMER; DELIVERY; POLY(N-ISOPROPYLACRYLAMIDE); DRUG; CHAINS;

D O I：

10.1039/b911986h

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Responsive polymeric nanoparticles composed of hybrid block co-polymers were prepared from biocompatible components that displayed rapid, tunable and multiply reversible transitions in response to change of temperature.

引用

页码：6068 / 6070

页数：3

共 27 条

[21]

Nano-oncology: drug delivery, imaging, and sensing [J].

Portney, NG ;

Ozkan, M .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2006, 384 (03) :620-630

[22]

Colloidal stability and drug incorporation aspects of micellar-like PLA-PEG nanoparticles [J].

Riley, T ;

Govender, T ;

Stolnik, S ;

Xiong, CD ;

Garnett, MC ;

Illum, L ;

Davis, SS .

COLLOIDS AND SURFACES B-BIOINTERFACES, 1999, 16 (1-4) :147-159

[23]

Cell up-take control of gold nanoparticles functionalized with a thermoresponsive polymer [J].

Salmaso, Stefano ;

Caliceti, Paolo ;

Amendola, Vincenzo ;

Meneghetti, Moreno ;

Magnusson, Johannes Pall ;

Pasparakis, George ;

Alexander, Cameron .

JOURNAL OF MATERIALS CHEMISTRY, 2009, 19 (11) :1608-1615

[24]

Enzyme responsive polymer hydrogel beads [J].

Thornton, PD ;

McConnell, G ;

Ulijn, RV .

CHEMICAL COMMUNICATIONS, 2005, (47) :5913-5915

[25]

Cytotoxicity of thermosensitive polymers poly(N-isopropylacrylamide), poly(N-vinylcaprolactam) and amphiphilically modified poly(N-vinylcaprolactam) [J].

Vihola, H ;

Laukkanen, A ;

Valtola, L ;

Tenhu, H ;

Hirvonen, J .

BIOMATERIALS, 2005, 26 (16) :3055-3064

[26]

Biodegradable Thermoresponsive Microparticle Dispersions for Injectable Cell Delivery Prepared Using a Single-Step Process [J].

Wang, Wenxin ;

Liang, He ;

Al Ghanami, Racha Cheikh ;

Hamilton, Lloyd ;

Fraylich, Michael ;

Shakesheff, Kevin M. ;

Saunders, Brian ;

Alexander, Cameron .

ADVANCED MATERIALS, 2009, 21 (18) :1809-+

[27]

The Coil-to-Globule-to-Coil Transition of Linear Polymer Chains in Dilute Aqueous Solutions: Effect of Intrachain Hydrogen Bonding [J].

Zhou, Kejin ;

Lu, Yijie ;

Li, Junfang ;

Shen, Lei ;

Zhang, Guangzhao ;

Xie, Zuowei ;

Wu, Chi .

MACROMOLECULES, 2008, 41 (22) :8927-8931

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