Recognition of Mismatched Base Pairs in DNA

被引：44

作者：

Nakatani, Kazuhiko ^{[1
]}

机构：

[1] Osaka Univ, Inst Sci & Ind Res, Osaka 5670047, Japan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2009年 / 82卷 / 09期

关键词：

GUANINE-GUANINE MISMATCHES; HUMAN TELOMERIC SEQUENCE; NAPHTHYRIDINE DIMER; HUMAN-CHROMOSOMES; MOLECULAR GLUE; BINDING; REPEAT; BULGE; FORM; POLYMORPHISM;

D O I：

10.1246/bcsj.82.1055

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mismatch binding ligand (MBL) selectively binds to mismatched base pairs with discrimination of the nucleotide bases composing the mismatch. This review focuses on the inside story regarding the molecular design of MBL and its function, and potential application in genomic science.

引用

页码：1055 / 1069

页数：15

共 68 条

[11] Molecular recognition of DNA by small molecules [J].

Dervan, PB .

BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (09) :2215-2235

[12] Photoswitchable molecular glue for DNA [J].

Dohno, Chikara ;

Uno, Shin-Nosuke ;

Nakatani, Kazuhiko .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (39) :11898-+

[13]

GACY AM, 1995, CELL, V81, P533

[14] Analysis of mismatched DNA by mismatch binding ligand (MBL)-Sepharose affinity chromatography [J].

Goto, Yuki ;

Suda, Hitoshi ;

Kobori, Akio ;

Nakatani, Kazuhiko .

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2007, 388 (5-6) :1165-1173

[15] Small-molecule binding to the nonquadruplex form of the human telomeric sequence [J].

Goto, Yuki ;

Hagihara, Shinya ;

Hagihara, Masaki ;

Nakatani, Kazuhiko .

CHEMBIOCHEM, 2007, 8 (07) :723-726

[16] Telomere length regulation [J].

Greider, CW .

ANNUAL REVIEW OF BIOCHEMISTRY, 1996, 65 :337-365

[17] Ligand-stabilized hairpin structures interfere with elongation of human telomere [J].

Hagihara, Masaki ;

Goto, Yuki ;

Nakatani, Kazuhiko .

CHEMBIOCHEM, 2008, 9 (04) :510-513

[18] Detection of guanine-adenine mismatches by surface plasmon resonance sensor carrying naphthyridine-azaquinolone hybrid on the surface [J].

Hagihara, S ;

Kumasawa, H ;

Goto, Y ;

Hayashi, G ;

Kobori, A ;

Saito, I ;

Nakatani, K .

NUCLEIC ACIDS RESEARCH, 2004, 32 (01) :278-286

[19] A DNA polymerase stop assay for G-quadruplex-interactive compounds [J].

Han, HY ;

Hurley, LH ;

Salazar, M .

NUCLEIC ACIDS RESEARCH, 1999, 27 (02) :537-542

[20] Intercalative G-tetraplex stabilization of telomeric DNA by a cationic porphyrin [J].

Haq, I ;

Trent, JO ;

Chowdhry, BZ ;

Jenkins, TC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (09) :1768-1779

← 1 2 3 4 5 6 7 →