On the application potential of gold nanoparticles in nanoelectronics and biomedicine

被引:225
作者
Homberger, Melanie
Simon, Ulrich [1 ]
机构
[1] Rhein Westfal TH Aachen, Inst Inorgan Chem, D-52074 Aachen, Germany
来源
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES | 2010年 / 368卷 / 1915期
关键词
gold cluster; nanoelectronics; single-electron tunnelling; cytotoxicity; biomedical applications; assembly principles; SINGLE-ELECTRON TRANSISTOR; STABILIZED METAL-CLUSTERS; BUILDING-BLOCKS; CRYSTAL-STRUCTURE; CHARGE-TRANSPORT; COLLOID SCIENCE; AU-55; CLUSTERS; DNA; SIZE; LIGAND;
D O I
10.1098/rsta.2009.0275
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Ligand-stabilized gold nanoparticles (AuNPs) are of high interest to research dedicated to future technologies such as nanoelectronics or biomedical applications. This research interest arises from the unique size-dependent properties such as surface plasmon resonance or Coulomb charging effects. It is shown here how the unique properties of individual AuNPs and AuNP assemblies can be used to create new functional materials for applications in a technical or biological environment. While the term technical environment focuses on the potential use of AuNPs as subunits in nanoelectronic devices, the term biological environment addresses issues of toxicity and novel concepts of controlling biomolecular reactions on the surface of AuNPs.
引用
收藏
页码:1405 / 1453
页数:49
相关论文
共 172 条
[1]   Direct Electrochemistry of Horseradish Peroxidase-Gold Nanoparticles Conjugate [J].
Ahirwal, Gautham Kumar ;
Mitra, Chanchal K. .
SENSORS, 2009, 9 (02) :881-894
[2]   Intrinsic multistate switching of gold clusters through electrochemical gating [J].
Albrecht, Tim ;
Mertens, Stijn F. L. ;
Ulstrup, J. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (29) :9162-9167
[3]   Semiconductor clusters, nanocrystals, and quantum dots [J].
Alivisatos, AP .
SCIENCE, 1996, 271 (5251) :933-937
[4]   Organization of 'nanocrystal molecules' using DNA [J].
Alivisatos, AP ;
Johnsson, KP ;
Peng, XG ;
Wilson, TE ;
Loweth, CJ ;
Bruchez, MP ;
Schultz, PG .
NATURE, 1996, 382 (6592) :609-611
[5]   Construction and characterization of a gold nanoparticle wire assembled using Mg2+-dependent RNA-RNA interactions [J].
Bates, AD ;
Callent, BP ;
Cooper, JM ;
Cosstick, R ;
Geary, C ;
Glidle, A ;
Jaeger, L ;
Pearson, JL ;
Proupín-Pérez, M ;
Xu, CG ;
Cumming, DRS .
NANO LETTERS, 2006, 6 (03) :445-448
[6]   Electrostatic trapping of single conducting nanoparticles between nanoelectrodes [J].
Bezryadin, A ;
Dekker, C ;
Schmid, G .
APPLIED PHYSICS LETTERS, 1997, 71 (09) :1273-1275
[7]   In-situ electrical addressing of one-dimensional gold nanoparticle assemblies [J].
Blech, Kerstin ;
Noyong, Michael ;
Juillerat, Frederic ;
Nakayama, Tomonobu ;
Hofmann, Heinrich ;
Simon, Ulrich .
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2008, 8 (01) :461-465
[8]   Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity [J].
Boisselier, Elodie ;
Astruc, Didier .
CHEMICAL SOCIETY REVIEWS, 2009, 38 (06) :1759-1782
[9]   Oxidation-resistant gold-55 clusters [J].
Boyen, HG ;
Kästle, G ;
Weigl, F ;
Koslowski, B ;
Dietrich, C ;
Ziemann, P ;
Spatz, JP ;
Riethmüller, S ;
Hartmann, C ;
Möller, M ;
Schmid, G ;
Garnier, MG ;
Oelhafen, P .
SCIENCE, 2002, 297 (5586) :1533-1536
[10]   Gold nanoparticle decoration of DNA on silicon [J].
Braun, G ;
Inagaki, K ;
Estabrook, RA ;
Wood, DK ;
Levy, E ;
Cleland, AN ;
Strouse, GF ;
Reich, NO .
LANGMUIR, 2005, 21 (23) :10699-10701