Less common applications of monoliths: Preconcentration and solid-phase extraction

被引:177
作者
Svec, Frantisek [1 ]
机构
[1] EO Lawrence Berkeley Natl Lab, Mol Foundry, Berkeley, CA 94720 USA
来源
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2006年 / 841卷 / 1-2期
关键词
monolith; solid-phase extraction; silica; polymer; capillary; microchip;
D O I
10.1016/j.jchromb.2006.03.055
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Monolithic materials are finding their place in a variety of fields. While liquid chromatography is the most emphasized use of this new category of porous media, some other just as important applications are eclipsed by the success of monolithic columns. This review article describes all current facets of use of monoliths in preconcentration and solid-phase extraction. In addition to the typical off line use that does not seem to be the main stream application for the monolithic materials, in-line connection of the preconcentration with HPLC, electrochromatography, electrophoresis, enzymatic digestion, as well as its applications in microfluidics are presented. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:52 / 64
页数:13
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