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Mitochondrial control of cell death

被引：2713
作者：
Kroemer, G
Reed, JC
机构：
[1] Inst Gustave Roussy, CNRS, ULR 1599, F-94805 Villejuif, France
[2] Burnham Inst, La Jolla, CA 92037 USA
来源：
NATURE MEDICINE | 2000年 / 6卷 / 05期
关键词：
D O I：
10.1038/74994
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In many instances, permeabilization of mitochondrial membranes is a rate-limiting step of apoptotic or necrotic cell demise. This has important consequences for the pathophysiology of cell death, as well as for its pharmacological control.
引用
收藏
页码：513 / 519
页数：7
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