Enantioselective Friedel-Crafts reaction of electron-rich alkenes catalyzed by chiral bronsted acid

被引：307

作者：

Terada, Masahiro ^{[1
]}

Sorimachi, Keiichi ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Sendai, Miyagi 9808578, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 02期

关键词：

D O I：

10.1021/ja0678166

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present the first enantioselective catalysis of the Friedel-Crafts reaction via activation of electronrich multiple bonds by a chiral Br nsted acid. The reaction of various indole derivatives with a broad range of substituted enecarbamates affords the corresponding Friedel-Crafts products in high yield and enantioselectivity.

引用

页码：292 / 293

页数：2

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