The synthesis of chiral cyanohydrins by oxynitrilases

被引：87

作者：

Griengl, H

Schwab, H

Fechter, M

机构：

[1] Graz Tech Univ, Inst Organ Chem, SFB Biocatalysis, Austrian Sci Fund, A-8010 Graz, Austria

[2] Graz Tech Univ, Inst Biotechnol, SFB Biocatalysis, Austrian Sci Fund, A-8010 Graz, Austria

来源：

TRENDS IN BIOTECHNOLOGY | 2000年 / 18卷 / 06期

关键词：

D O I：

10.1016/S0167-7799(00)01452-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Enantiomerically pure cyanohydrins are important synthetic intermediates for pharmaceuticals and agrochemicals. They are produced by enzyme-catalysed synthesis using oxynitrilases, Sufficient quantities of enzyme are available via cheap natural sources and there have been recent advances in overexpression production of cyanohydrins on an industrial scale.

引用

页码：252 / 256

页数：5

共 61 条

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