Microwave Multicomponent Synthesis

被引:110
作者
Hugel, Helmut M. [1 ]
机构
[1] RMIT Univ, Sch Appl Sci, Melbourne, Vic 3001, Australia
来源
MOLECULES | 2009年 / 14卷 / 12期
关键词
one-pot reactions; synthetic methods; microwave technology; multicomponent reactions; ASSISTED COMBINATORIAL SYNTHESIS; POT TOTAL SYNTHESES; EFFICIENT SYNTHESIS; PARALLEL SYNTHESIS; DERIVATIVES; LIBRARY; FACILE; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES; 1,4-DIHYDROPYRIDINES; HETEROCYCLES;
D O I
10.3390/molecules14124936
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the manner that very important research is often performed by multidisciplinary research teams, the applications of multicomponent reactions involving the combination of multiple starting materials with different functional groups leading to the higher efficiency and environmentally friendly construction of multifunctional/complex target molecules is growing in importance. This review will explore the advances and advantages in microwave multicomponent synthesis (MMS) that have been achieved over the last five years.
引用
收藏
页码:4936 / 4972
页数:37
相关论文
共 59 条
[1]   Studies on reactions of pyrimidine compounds. 2. Microwave-assisted synthesis of 1,2,3,4-tetrahydro-2-thioxopyrimidine derivatives [J].
Aklbas, Esvet ;
Aslanoglu, Furgan .
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2008, 183 (01) :82-89
[2]  
[Anonymous], TETRAHEDRON LETT
[3]  
Bagley MC, 2006, TOP HETEROCYCLIC CHE, V1, P31
[4]   Multicomponent reactions to form heterocycles by microwave-assisted continuous flow organic synthesis [J].
Bremner, W. Stacy ;
Organ, Michael G. .
JOURNAL OF COMBINATORIAL CHEMISTRY, 2007, 9 (01) :14-16
[5]   One-pot multicomponent synthesis of 2,3-dihydropyrans: new access to furanose-pyranose 1,3-C-C-linked-disaccharides [J].
Castagnolo, Daniele ;
Botta, Lorenzo ;
Botta, Maurizio .
TETRAHEDRON LETTERS, 2009, 50 (14) :1526-1528
[6]   Tuning of chemo- and regioselectivities in multicomponent condensations of 5-aminopyrazoles, dimedone, and aldehydes [J].
Chebanov, Valentin A. ;
Saraev, Vyacheslav E. ;
Desenko, Sergey M. ;
Chernenko, Vitaliy N. ;
Knyazeva, Irina V. ;
Groth, Ulrich ;
Glasnov, Tortia N. ;
Kappe, C. Oliver .
JOURNAL OF ORGANIC CHEMISTRY, 2008, 73 (13) :5110-5118
[7]   One-pot, multicomponent route to pyrazoloquinolizinones [J].
Chebanov, Valentin A. ;
Saraev, Vyacheslav E. ;
Desenko, Sergey M. ;
Chemenko, Vitaliy N. ;
Shishkina, Svetlana V. ;
Shishkin, Oleg V. ;
Kobzar, Kiril M. ;
Kappe, C. Oliver .
ORGANIC LETTERS, 2007, 9 (09) :1691-1694
[8]   Parallel synthesis of strongly fluorescent polysubstituted 2,6-dicyanoanilines via microwave-promoted multicomponent reaction [J].
Cui, SL ;
Lin, XF ;
Wang, YG .
JOURNAL OF ORGANIC CHEMISTRY, 2005, 70 (07) :2866-2869
[9]   A Tandem One-Pot, Microwave-Assisted Synthesis of Regiochemically Differentiated 1,2,4,5-Tetrahydro-1 4-benzodiazepin-3-ones [J].
De Silva, Ravindra A. ;
Santra, Soumava ;
Andreana, Peter R. .
ORGANIC LETTERS, 2008, 10 (20) :4541-4544
[10]   Microwave-assisted multicomponent synthesis of aza-, diaza-, benzo-, and dibenzofluorenedione derivatives [J].
Defant, Andrea ;
Guella, Graziano ;
Mancini, Ines .
SYNTHETIC COMMUNICATIONS, 2008, 38 (17) :3003-3016